After attending a forum in DC where Hillary Clinton was the keynote speaker, The New Yorker's David Remnick strongly believes she will run for president in 2016.
...there was much chatter about what Clinton would do after she steps down from the Cabinet next month—get a haircut; take a few weeks sleeping off jet lag at Canyon Ranch; read the polls and the political landscape; do good works; do good works for the good people of, say, Iowa—and so on. Everyone had a theory of which they were one hundred percent certain. There wasn’t much doubt about the ultimate direction. 2007-8 was but a memory and 2016 was within sight. She’s running.
If she does, you can bet the president (as long as his poll numbers are strong) will do some hardcore campaigning in exchange for Bill Clinton's dedicated work this year. But before that, the president will have to tell Joe Biden that it's not his year -- that Hillary is the White House's candidate.