As I pointed out in my liveblog last night, the biggest Palin lie was probably this one:
Listening to [Obama] speak, it's easy to forget that this is a man who has authored two memoirs but not a single major law or even a reform, not even in the state senate.
I also noted that he has introduced at least 150 pieces of legslation in the U.S. Senate. Sullivan has a complete accounting here.
UPDATE: Here's a thorough debunking of Palin's lies from last night.